About Dr. Paresh Doshi

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Prof. (Dr.) Doshi is the Director of Neurosurgery, Stereotactic and Functional Neurosurgery, and a newly established department of Restorative and Regenerative Medicine at the Jaslok Hospital and Research Centre, Mumbai. He established the first stereotactic and functional neurosurgery department in India in 1998. He is in charge of the Stereotactic and Functional Neurosurgery program at Jaslok Hospital, which has been established since 1998.

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About Dr.Paresh Doshi

Prof. Doshi, M.S., MCh.PhD is a functional neurosurgeon practicing at the Jaslok Hospital and Research Centre, in Mumbai. Dr Doshi is amongst one of the best neurosurgeons in Mumbai, India, and a pioneer of stereotactic and functional neurological surgery in India.

Since 1998, he has led the Stereotactic and Functional Neurosurgery program at Jaslok Hospital, which was the only dedicated and comprehensive Stereotactic and Functional Neurosurgical program in India at that time.

He has conducted over 1000 Stereotactic surgeries including 650 deep brain stimulation (DBS) surgeries. He has been credited with several firsts in the world and India:

ONLY CENTRE IN THE WORLD

  • Simultaneous PPN and STN DBS for PD/PSP patients
  • PPN and STN Stimulation for PSP
  • Czi Stimulation for SCA 12

FIRST IN ASIA-AUSTRALIA

1. Deep Brain Stimulation for Depression

FIRST IN INDIA

1. Pallidotomy for Parkinson’s disease
2. DBS for Parkinson’s disease
3. DBS for Persistent vegetative state
4. Occipital Nerve Stimulation for Migraine
5. Thalamotomy for Writer’s Dystonia
6. Capsulotomy for OCD
7. DBS for OCD
8. DBS for Tourette Syndrome
9. SCS stimulation for minimally conscious state
10. Diaphragmatic stimulation for diaphragm paralysis
11. Motor cortex stimulation for post stroke pain
12. Operated the youngest and the oldest Parkinson’s disease patients in India
13. First surgery with dual pacemakers, one for cardiac and another for Parkinson’s disease
14. DBS in patient with Autism
15. Peripheral nerve stimulation
16. Cervical rhizotomy for dystonia

Positions held in Academic society:

1. President of The Neuromodulation Society
2. Past President of Indian Society of Stereotactic and Functional Neurosurgery
3. Secretary, World society for stereotactic and Functional Neurosurgery
4. Director, International Neuromodulation society
5. Board Member of Asian-Australasian society for stereotactic and Functional Neurosurgery
6. Board Member of the WSSFN task force on Psychiatric disorders surgery
7. Course Director of EEPIN, London.

Education Of Prof Dr. Paresh Doshi

Doshi earned his M.B.B.S. from Smt. N. H. L. Municipal Medical College, Ahmedabad, India, and hisM.S. (General Surgery) from Sheth K. M. School of Post Graduate Medicine and Research, Ahmedabad, India. He did his M.Ch. (Neurosurgery) from T.N. Medical College, Bombay, India. Thereafter, Doshi underwent extensive training in the field of Stereotaxy and Functional Neurosurgery at the National Hospital for Neurology and Neurosurgery, Queen Square London, Maudsley, King’s College Hospital, London, and Newcastle General Hospital for 4 years. He then gained further exposure and experience with specific Movement Disorder surgeries in the USA, Netherlands, Sweden, France, and Austria, under eminent functional neurosurgeons like Prof. Benabid, Prof. Alesch, Prof. Hariz and many others. In 2024, recognizing his immense contribution to the field of functional neurosurgery in India, Rajasthan University of Health Sciences, conferred him a honorary PhD degree.

The career of Prof Dr. Paresh Doshi

Dr Doshi started his career in neurosurgery in India where he assisted, performed and supervised a large number of neurosurgical operations, including cases of head trauma, brain tumors, spinal surgeries, vascular neurosurgeries, pediatric neurosurgeries, radio-frequency lesions for pain, transsphenoidal, transoral surgeries, stereotaxy, etc.

He then moved to England to work as a clinical fellow with Professor Thomas, as part of his Stereotaxy and Functional Neurosurgery program. He gained experience in epilepsy surgery from the Maudsley Hospital and thereafter moved on to New Castle to continue his experience in general neurosurgery.

Dr Doshi then trained in movement disorder surgeries, under Dr. Marwan Hariz and Professor A. Bosch in Umeå (Sweden) and Amsterdam where he performed pallidotomies.

Subsequently, he worked with Prof. Benabid and Prof. Alesch, in Grenoble and Vienna to learn the art of deep brain stimulation, surgery. In 2003, he visited Lyon, France to obtain training in Spasticity from Prof. Marc Sindou.

In 1998, Doshi set up a Functional Neurosurgery Department at the Jaslok Hospital and Research Center in Mumbai, India, which is supported by well-trained neurologists and neurophysiologists and backed by a state-of-the-art neurophysiology and neuroradiology department.

The center is renowned for performing epilepsy surgeries, movement disorder surgeries, surgery for chronic pain and spasticity and a wide spectrum of movement disorder surgeries including thalamotomy, pallidotomy, subthalamic nucleus lesioning and deep brain stimulation.

He also started the Fellowship Training Program in Functional Neurosurgery where he has trained four neurosurgeons who are independently performing functional neurosurgeries and launched the Spasticity Program in 2004 and the Psychiatric Disorder surgery program in 2009.

He introduced the technique of stereotactic evacuation of intracerebral hematoma in Mumbai.

Dr Doshi is also known for operating on the oldest patient (82 years old) of Parkinson’s Disease in the world

Psychiatric Disorders

Parkinson’s Disease

Dr. Paresh Doshi is one of the world’s Best neurosurgeon and expert on Parkinson’s Disease and frequently promotes awareness of its treatment across the nation.

He has performed many path-breaking surgeries on patients suffering from acute and rare cases of PD and is at the forefront of medical research in this field. He is also known for conducting brain surgery on India’s youngest PD patient.

World Parkinson’s day is celebrated on 11 th April 2019. The aim is to create an awareness of Parkinson’s disease, educate by the knowledge and how it can affect a person gradually. Jaslok Hospital & Dr. Paresh Doshi will be organizing  Free Parkinson’s Disease Camp for two days on 13 & 14 April 2019 at Jaslok Hospital. For more details, call on 9930960960.

Deep Brain Surgery

Dr Doshi is a pioneer/specialist in the field of deep brain stimulation(DBS). He is the first neurosurgeon to perform DBS surgery in India and has performed the largest number of DBS surgeries in India.

performing DBS surgery

He is also the only Neurosurgeon to perform DBS in patients with cardiac pacemakers. Doshi is also credited with the largest number of stereotactic procedures performed by a single person in India, with a success rate of greater than 95%.

He has experience of 250 movement disorders surgeries of which 500 are DBS surgeries.

Research

Dr. Paresh Doshi has been at the forefront of several research projects, including Parkinson’s Disease. He evaluated the outcome of movement disorder surgery and developed newer surgical targets for the treatment of movement disorders.

He evaluated of the role of autologous (transplanted) mesenchymal stem cell therapy for patients with advanced Parkinson’s disease, evaluated hardware and surgical complications of deep brain stimulation surgery in India, studied and identified the most effective targeting protocol for Subthalamic nucleus stimulation.

His team also published a study in an international medical journal about arresting the debilitating effects of the progressive supranuclear palsy, a debilitating condition that leaves patients wheelchair bound in less than three years.

Here are some of his notable publications:

  1. Nucleus Accumbens (NAc) DBS for obsessive compulsive disorder and aggression in an autistic patient: a case report and hypothesis of the role of NAc in autism and co-morbid symptoms. Doshi PK, Hegde A, Desai A. World Neurosurg. 2019 Feb 21. pii: S1878-8750(19)30431-0
  2. A comparative study of bilateral subthalamic nucleus DBS in Parkinson’s disease in young versus old: A single institutional study. Vats A, Amit A, Doshi P. J Clin Neurosci. 2019;70:85-91. doi:10.1016/j.jocn.2019.08.065
  3. Multicentric high grade oligodendroglioma: a rare entity. Vats A, Amit A, Doshi P. Br J Neurosurg. 2019;33(6):678-680. doi:10.1080/02688697.2017.1396582
  4. Surgical and Hardware Complications of Deep Brain Stimulation—A Single Surgeon Experience of 519 Cases Over 20 Years. Doshi P.K., Rai N., Das D. 2021. Neuromodulation 2021; E-pub ahead of print. DOI:10.1111/ner.13360
  5. Indian guidelines on neurosurgical interventions in psychiatric disorders. Doshi PK, Arumugham SS, Bhide A, et al. Indian J Psychiatry. 2019 Jan-Feb;61(1):13-21

Awards and Honors

Dr Doshi was awarded the Young Achiever’s Award by the Indo-American Society, Mumbai in 2002. He was also named “Top five medical specialists of Mumbai” by Times of India group in 2005, “Best Neurosurgeon and neurosciences department” by CNN IBN group in 2012 and awarded the “Excellence in Neurosciences” award by Medscape India in 2012.

Dr Doshi was invited as a CME speaker to talk on Functional Neurosurgery at the prestigious meetings of Neurological Society of India in 1996, 2001 and 2004; Indian Academy of Neurology (2002); World society of stereotactic and functional neurosurgery, Toronto, 2011, Asian society of Stereotactic, Functional and computer-assisted neurosurgery (Beijing, 2000, Taiwan 2004, Japan 2006, Hong Kong 2009 and Taiwan 2011); Asian and Pacific Parkinson’s disease Surgery Association meeting in Hong Kong (2001) and Indian Society of Stereotactic and Functional Neurosurgery (1999, 2000, 01,03 & 04,06,08,09,10,11), Congress of Neurological surgeon, USA (2009).

He also conducted workshops in Stereotaxy surgery and Movement disorders in 1993 (London, England), 2001 (Mumbai, India) and 2001 (Indore, India).