At Jaslok Hospital in Dr. Paresh Doshi’s Functional Neurosurgery department, we offer advanced MRgFUS treatment in Mumbai, a non-invasive procedure for essential tremor and tremor-dominant Parkinson’s disease. While MRgFUS is highly effective for select patients, Deep Brain Stimulation (DBS) remains the gold standard for long-term symptom control, bilateral treatment, and flexible adjustment.
What is MRgFUS?
sMagnetic Resonance-Guided Focused Ultrasound (MRgFUS) is a cutting-edge, non-invasive neurosurgical procedure that uses focused ultrasound waves combined with real-time MRI guidance to target brain areas responsible for tremors.
- Non-invasive and scar-free
- Performed under MRI guidance for maximum precision
- Reduces tremors immediately, often during the procedure
Outpatient procedure with minimal recovery
How MRgFUS Works
- Comprehensive assessment – MRI and neurological evaluation.
- Precise targeting – MRI identifies the exact brain region causing tremors.
- Focused ultrasound delivery – Controlled energy ablates the targeted tissue.
- Real-time monitoring – MRI thermometry ensures safety.
Immediate results – Many patients notice tremor improvement during or right after the procedure.
Benefits of MRgFUS
- Non-invasive – No cuts, no implants
- Quick recovery – Most patients return home the same day
- Immediate results – Tremor reduction visible during treatment
Precision targeting – Protects surrounding brain tissue
Limitations of MRgFUS
While effective, MRgFUS has limitations compared to DBS:
- Unilateral treatment only – Only one side of the brain can be treated safely
- Permanent and irreversible – Cannot be adjusted or modified later
Limited flexibility – Less suitable for progressive or severe disease
MRgFUS vs Deep Brain Stimulation (DBS)
Feature | MRgFUS | Deep Brain Stimulation (DBS) |
Procedure | Non-invasive, incision-free | Minimally invasive, electrode-based |
Reversibility | Irreversible | Fully reversible and adjustable |
Treatment sides | One side only | Can treat both sides safely |
Long-term control | Fixed results | Adjustable for disease progression |
Customization | None | Fine-tune stimulation anytime |
Ideal for | Mild tremor, patients unfit for surgery | Moderate to severe Parkinson’s, dystonia, essential tremor, complex cases |
Durability | May plateau over time | Long-term symptom control and quality of life |
MRI compatibility | Full MRI access | MRI-conditional systems available |
Insight: MRgFUS is suitable for select patients, but DBS provides superior long-term results, adjustability, and flexibility — making it the preferred choice for most movement disorders.
Who is a Candidate for MRgFUS?
MRgFUS is ideal for patients with:
- Essential Tremor (ET)
- Tremor-dominant Parkinson’s disease when medications fail
Eligibility requires:
- Detailed neurological evaluation
- MRI for precise targeting
- Assessment of overall health
Note: MRgFUS is best for unilateral, mild-to-moderate tremor, whereas DBS is preferred for bilateral or advanced symptoms.
What to Expect During the Procedure
- Preparation – Blood tests, MRI scans, and pre-procedure assessment
- Procedure – Patient is awake; head stabilized; ultrasound energy delivered in phases
- Recovery – Typically outpatient; patients can resume normal activity within a day
Safety: Minor side effects like warmth, mild discomfort, numbness, or imbalance may occur but are usually temporary.
Why Choose Dr. Paresh Doshi for MRgFUS or DBS?
Led by Prof. Dr. Paresh Doshi, India’s leading functional neurosurgeon with decades of experience, our center combines:
- Advanced MRgFUS and DBS technology
- Personalized, patient-focused care
- Expertise in tremors, Parkinson’s disease, dystonia, and complex movement disorders
We evaluate each patient carefully to recommend the most effective treatment — whether MRgFUS or DBS — ensuring maximum symptom improvement and long-term quality of life.
Schedule Your Consultation Today
If you or a loved one are exploring MRgFUS or DBS treatment in Mumbai, schedule a consultation to determine the safest and most effective option.
Call/Whatsapp: 9930990777
email: Paresh.neuro@gmail.com
